Assoc. Prof. Dr. Tolga Göktürk
TR

Publications

Peer-reviewed journal articles, book chapters, and other academic publications.

SCIE-Indexed Journal Articles

27) Hydrazone-Oxime Ni(II) Complexes: Crystal Structures, DNA Binding, DNA Cleavage and Topoisomerase Inhibition
Topkaya, C., Hökelek, T., Göktürk, T., Zengin, T. & Güp, R.
Journal of Coordination Chemistry, 79(13), 1693–1714 · 2026
DOI: 10.1080/00958972.2026.2705463
Graphical Abstract
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26) Structure-Activity Modulation of Nitro-Substituted Bis(acylhydrazone) Ligands by O-Alkylation in Breast Cancer Models
Topkaya, C., Hökelek, T., Göktürk, T., Güp, R. & Demircan, T.
Journal of Molecular Structure, 146934 · 2026
DOI: 10.1016/j.molstruc.2026.146934
Graphical Abstract
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25) Triazole-Based Hydrazone-Oxime Ligands with Potent and Selective Anticancer Activity Against Colorectal Cancer: Structural Insights, Topoisomerase IIα Inhibition and SAR Analysis
Göktürk, T.
Journal of Molecular Structure, 146096 · 2026
DOI: 10.1016/j.molstruc.2026.146096
Graphical Abstract
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24) Synthesis, Structural Characterization and Anticancer Activity of a New 1,2,3-Triazole Derivative: in silico Investigations and Cytotoxicity
Canlı, E., Göktürk, T., Güp, R., Hökelek, T. & Çetin, E. S.
Journal of Molecular Structure, 145017 · 2026
DOI: 10.1016/j.molstruc.2025.145017
Graphical Abstract
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23) Syntheses of Novel 1,2,3-Triazole-Based Schiff Base Ligands and Their Co(II) Complexes: DNA/BSA Binding, DNA Cleavage, Topoisomerase IIα Inhibition and Cytotoxicity Studies
Göktürk, T., Hökelek, T., Karaman, S. G., Ağar, H., Aksu, E. N., Çetin, E. S., Canlı, E. & Güp, R.
Inorganic Chemistry Communications, 182, 115544 · 2025
DOI: 10.1016/j.inoche.2025.115544
Graphical Abstract
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22) Synthesis, Crystal Structure, and Electrochemical Investigation of a New Trithiane Derived Compound for High-Performance Supercapacitors
Özen, A. A., Göktürk, T., Hökelek, T., Güp, R., Topkaya, C., Bilge, A. G. & Aslan, S.
ACS Omega, 10(36), 41595–41607 · 2025
DOI: 10.1021/acsomega.5c05184
Graphical Abstract
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21) Nickel(II) Complex of p-tolylglyoxime: Structural Investigations, ADMET Predictions, in-silico DNA and HSA Binding Assessments
Göktürk, T., Topkaya, C., Zengin, T., Hökelek, T., Çağlar, U. & Güp, R.
Journal of Coordination Chemistry, 78(10), 1160–1179 · 2025
DOI: 10.1080/00958972.2025.2493712
Graphical Abstract
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20) Crystal Structure Analysis and Anticancer Potential of a Naphthalene-Based Schiff Base Against Breast Cancer
Göktürk, T., Demircan, T., Hökelek, T., Yavuz, M., Güp, R. & Topkaya, C.
Acta Chimica Slovenica, 72(2), 299–308 · 2025
DOI: 10.17344/acsi.2025.9191
Graphical Abstract
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19) Role of Acetate/Benzoate Substituents on the Anticancer Activities, In Vitro and In Silico DNA/BSA Interactions of New 1,4-Disubstituted 1,2,3-Triazole Derivatives
Göktürk, T., Sakallı Çetin, E., Pekel, H., Şensoy, O., Aksu, E. N., Hökelek, T. & Güp, R.
Journal of Molecular Structure, 1338, 142273 · 2025
DOI: 10.1016/j.molstruc.2025.142273
Graphical Abstract
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18) A New Cu(II) Complex With 1,3-Dimethyl-5-Acetyl-Barbituric Acid: Synthesis, Crystal Structure, DNA/BSA Binding Activities, ADME Predictions, and Anticancer Activities
Göktürk, T.
Applied Organometallic Chemistry, 39(1), e70006 · 2025
DOI: 10.1002/aoc.70006
Graphical Abstract
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17) Effects of electron donating and withdrawing substituents on crystal structures, cytotoxicity and in silico DNA interactions of isatinoxime Schiff base ligands
Göktürk, T., Güp, R., Zengin, T., Hökelek, T., Aksu, E. N., Öztürk, F. S. & Sakallı Çetin, E.
Research on Chemical Intermediates, 51, 433–457 · 2025
DOI: 10.1007/s11164-024-05464-6
Graphical Abstract
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16) Novel benzohydrazide derivative as a potential anticarcinogenic agent for breast cancer: Synthesis, crystal structure, in vitro and in silico assessments
Göktürk, T., Topkaya, C., Demircan, T., Akgül, S., Hökelek, T. & Güp, R.
Journal of Molecular Structure, 1323, 140673 · 2025
DOI: 10.1016/j.molstruc.2024.140673
Graphical Abstract
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15) One-step synthesis of 2-Methyl-2,4-Diphenyl-2,3-Dihydro-1H-Benzo[b][1,4]diazepine: Investigating crystal structure, Hirshfeld surface analysis and supercapacitor applications
Topkaya, C., Hökelek, T., Aslan, S., Göktürk, T., Kıncal, S., Çağlar, U. & Güp, R.
Journal of Molecular Structure, 1318, 139461 · 2024
DOI: 10.1016/j.molstruc.2024.139461
14) Crystal structure, Hirshfeld surface analysis, crystal voids, interaction energy calculations, energy frameworks and supercapacitor applications of isatin hydrazone ligand
Topkaya, C., Hökelek, T., Aslan, S., Özen, A. A., Kıncal, S., Göktürk, T. & Güp, R.
Journal of Molecular Structure, 1316, 139014 · 2024
DOI: 10.1016/j.molstruc.2024.139014
13) A New 1,2,4-Triazine-N-Oxide Compound: Synthesis, Crystal Structure, Hirshfeld Surface Analysis and Supercapacitor Applications
Topkaya, C. G., Aslan, S., Göktürk, T., Kıncal, S., Hökelek, T. & Güp, R.
Journal of Molecular Structure, 1295, 136689 · 2024
DOI: 10.1016/j.molstruc.2023.136689
Graphical Abstract
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12) Serendipitous Synthesis of an Octahedral Ni(II) Complex: Single Crystal Structure, Hirshfeld Surface and Voids Analysis
Göktürk, T., Topkaya, C. G., Hökelek, T. & Güp, R.
Journal of Structural Chemistry, 65(1), 15–27 · 2024
DOI: 10.26902/JSC_id119753
Graphical Abstract
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11) Synthesis, Structural Investigations, DNA/BSA Interactions, Molecular Docking Studies, and Anticancer Activity of a New 1,4-Disubstituted 1,2,3-Triazole Derivative
Göktürk, T., Sakallı Çetin, E., Hökelek, T., Pekel, H., Şensoy, O., Aksu, E. N. & Güp, R.
ACS Omega, 8(35), 31839–31856 · 2023
DOI: 10.1021/acsomega.3c03355
Graphical Abstract
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10) Synthesis, Spectroscopic Characterization, Crystal Structure and Biological Properties of Novel Co-Crystal Copper(II) Complex Containing Dioxime Ligand
Topkaya, C. G., Çetin, E. S., Göktürk, T., Kıncal, S., Hökelek, T. & Güp, R.
Inorganic Chemistry Communications, 155, 111040 · 2023
DOI: 10.1016/j.inoche.2023.111040
Graphical Abstract
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9) Synthesis, Crystal Structure, Hirshfeld Surface Analysis, DNA/BSA Interaction and Molecular Docking Studies of 2-(6-(4-chlorophenyl)-1,2,4-triazin-3-yl) quinoline
Göktürk, T., Zengin, T., Hökelek, T., Topkaya, C. G. & Güp, R.
Journal of Molecular Structure, 1292, 136128 · 2023
DOI: 10.1016/j.molstruc.2023.136128
Graphical Abstract
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8) Synthesis, Crystal Structure, Hirshfeld Surface Analysis and Interaction Energy and Energy Framework Studies of Novel Hydrazone Derivative Containing Barbituric Acid Moiety
Kıncal, S., Topkaya, C., Göktürk, T., Hökelek, T. & Güp, R.
Journal of Chemical Crystallography, 53(1), 81–92 · 2023
DOI: 10.1007/s10870-022-00945-1
Graphical Abstract
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7) In vitro DNA Interaction, Topoisomerase I/II Inhibition and Cytotoxic Properties of Polymeric Copper(II) Complex Bridged with Perchlorate Ion Containing N4-type Schiff Base Ligand
Topkaya, C., Göktürk, T., Hökelek, T., Sakallı Çetin, E., Kıncal, S. & Güp, R.
Journal of Molecular Structure, 1266, 133453 · 2022
DOI: 10.1016/j.molstruc.2022.133453
Graphical Abstract
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6) Syntheses, Crystal Structures, Hirshfeld Surface Analyses and Electrochemical Etoposide/Camptotechin Sensor Applications of Acetaldehyde Oxime Derivatives
Topkaya, C., Aslan, S., Hökelek, T., Göktürk, T., Kıncal, S., Altuntaş, D. B. & Güp, R.
Journal of Molecular Structure, 1265, 133339 · 2022
DOI: 10.1016/j.molstruc.2022.133339
Graphical Abstract
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5) New trinuclear nickel(II) complexes as potential topoisomerase I/IIα inhibitors: in vitro DNA binding, cleavage and cytotoxicity against human cancer cell lines
Göktürk, T., Topkaya, C., Sakallı Çetin, E. & Güp, R.
Chemical Papers, 76, 2093–2109 · 2022
DOI: 10.1007/s11696-021-02005-y
Graphical Abstract
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4) Synthesis, Crystal Structure, Hirshfeld Surface Analysis of Ethyl 4-(4-(2-Bromoethyl)-1H-1,2,3-triazol-1-yl) benzoate
Göktürk, T., Hökelek, T. & Güp, R.
Crystallography Reports, 66(6), 977–984 · 2021
DOI: 10.1134/S1063774521060109
3) Synthesis, characterization and DNA interaction of Cu(II) complexes with hydrazone-Schiff base ligands bearing alkyl quaternary ammonium salts
Şengül, E. E., Göktürk, T., Topkaya, C. G. & Güp, R.
Journal of the Chilean Chemical Society, 65(2), 4754–4758 · 2020
DOI: 10.4067/S0717-97072020000204754
2) Synthesis and Characterization of Copper(II) Complexes with Aroylhydrazone Ligands Containing Quaternary Ammonium Salts: in Vitro DNA Binding and Nuclease Activity
Elif, E. Ş., Topkaya, C. G., Göktürk, T. & Güp, R.
Chinese Journal of Inorganic Chemistry, 36(7), 1333–1343 · 2020
DOI: 10.11862/CJIC.2020.149
1) Investigation of phenolic profiles and antioxidant activities of some Salvia species commonly grown in Southwest Anatolia using UPLC-ESI-MS/MS
Kıvrak, Ş., Göktürk, T., Kaya, E., Karababa, E. & Kıvrak, İ.
Food Science and Technology, 39, 423–431 · 2019
DOI: 10.1590/fst.32017

Book Chapter

The Usage Of Transition Metal Complexes In Electrochemical Sensor And Biosensor Applications
Aslan, S., Topkaya, C. G., Mamuk, A. E., Altuntaş, D. B. & Göktürk, T.
In Electrochemistry Volume 17, The Royal Society of Chemistry, pp. 152–180 · 2023